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The co-Principal efficacy endpoints were the p.c reduction in inflammatory lesion counts and percentage of subjects with results on IGA, defined as an IGA score of 0 (“clear”) or 1 ( “Practically distinct”) at Week 10. The efficacy success are shown in the following table:
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Oral metronidazole is noted to potenti-ate the anticoagulant outcome of coumarin and warfarin leading to a prolongation of prothrombin time. The impact of topical metronida-zole on prothrombin time is not really acknowledged.
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System by which metronidazole acts in link jnetogel the treatment method of rosacea is unfamiliar, but seems to include an anti-inflammatory result
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